Phytotherapy and oral chemotherapy, relations that are not without risks (results n°2)
Summary
The interactions between herbal medicines and oral chemotherapy represent a critical area of concern in oncology due to the narrow therapeutic margin of cancer treatments. These interactions can be pharmacokinetic—affecting drug absorption, metabolism, and elimination—or pharmacodynamic, altering the therapeutic effects of drugs. Herbal medicines, such as garlic or psyllium, may induce or inhibit cytochromes like CYP450, influencing chemotherapy efficacy or toxicity. A comprehensive analysis of plants and oral chemotherapy highlights potential risks, including toxicity, therapeutic failure, and adverse effects. Enhanced awareness and detailed cross-referencing of pharmacological data are crucial for ensuring patient safety and optimizing treatment outcomes.
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